miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions

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ID: 298045
2013
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Abstract
MicroRNAs (miRNAs) are small non-coding RNA molecules capable of negatively regulating gene expression to control many cellular mechanisms. The miRTarBase database (http://mirtarbase.mbc.nctu.edu.tw/) provides the most current and comprehensive information of experimentally validated miRNA-target interactions. The database was launched in 2010 with data sources for >100 published studies in the identification of miRNA targets, molecular networks of miRNA targets and systems biology, and the current release (2013, version 4) includes significant expansions and enhancements over the initial release (2010, version 1). This article reports the current status of and recent improvements to the database, including (i) a 14-fold increase to miRNA-target interaction entries, (ii) a miRNA-target network, (iii) expression profile of miRNA and its target gene, (iv) miRNA target-associated diseases and (v) additional utilities including an upgrade reminder and an error reporting/user feedback system.
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openalex_W2016106370 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sheng‐Da Hsu, Yu‐Ting Tseng, Sirjana Shrestha, Yu‐Ling Lin, Anas Khaleel, Chih‐Hung Chou, Chao-Fang Chu, Hsi‐Yuan Huang, Ching-Min Lin, Shu-Yi Ho, Ting-Yan Jian, Feng‐Mao Lin, Tzu‐Hao Chang, Shun‐Long Weng, Kuang‐Wen Liao, I‐En Liao, Chun-Chi Liu, Hsien‐Da Huang
Journal Nucleic Acids Research
Year 2013
DOI
10.1093/nar/gkt1266
URL
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