The InterPro database, an integrated documentation resource for protein families, domains and functional sites

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ID: 297764
2001
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Abstract
Signature databases are vital tools for identifying distant relationships in novel sequences and hence for inferring protein function. InterPro is an integrated documentation resource for protein families, domains and functional sites, which amalgamates the efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Each InterPro entry includes a functional description, annotation, literature references and links back to the relevant member database(s). Release 2.0 of InterPro (October 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification encoded by a total of 6804 different regular expressions, profiles, fingerprints and Hidden Markov Models. Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1 000 000 hits from 462 500 proteins in SWISS-PROT and TrEMBL). The database is accessible for text- and sequence-based searches at http://www.ebi.ac.uk/interpro/. Questions can be emailed to interhelp@ebi.ac.uk.
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openalex_W2166699767 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Rolf Apweiler
Journal Nucleic Acids Research
Year 2001
DOI
10.1093/nar/29.1.37
URL
https://academic.oup.com/nar/article-pdf/29/1/37/9905814/290037.pdf
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