Frailty: An Emerging Research and Clinical Paradigm--Issues and Controversies

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ID: 297324
2007
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Ranked #53 of 134 articles by views in the journals of gerontology series a, biological sciences and medical sciences

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Abstract
Clinicians and researchers have shown increasing interest in frailty. Yet, there is still considerable uncertainty regarding the concept and its definition. In this article, we present perspectives on key issues and controversies discussed by scientists from 13 different countries, representing a diverse range of disciplines, at the 2006 Second International Working Meeting on Frailty and Aging. The following fundamental questions are discussed: What is the distinction, if any, between frailty and aging? What is its relationship with chronic disease? Is frailty a syndrome or a series of age-related impairments that predict adverse outcomes? What are the critical domains in its operational definition? Is frailty a useful concept? The implications of different models and approaches are examined. Although consensus has yet to be attained, work accomplished to date has opened exciting new horizons. The article concludes with suggested directions for future research.
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openalex_W2099770557 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Howard Bergman, Leah M. Ferrucci, Jack M. Guralnik, David B. Hogan, S Hummel, Sathya Karunananthan, Christina Wolfson
Journal the journals of gerontology series a, biological sciences and medical sciences
Year 2007
DOI
10.1093/gerona/62.7.731
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