NCBI Reference Sequences (RefSeq): current status, new features and genome annotation policy

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ID: 296583
2011
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Abstract
The National Center for Biotechnology Information (NCBI) Reference Sequence (RefSeq) database is a collection of genomic, transcript and protein sequence records. These records are selected and curated from public sequence archives and represent a significant reduction in redundancy compared to the volume of data archived by the International Nucleotide Sequence Database Collaboration. The database includes over 16 000 organisms, 2.4 × 106 genomic records, 13 × 106 proteins and 2 × 106 RNA records spanning prokaryotes, eukaryotes and viruses (RefSeq release 49, September 2011). The RefSeq database is maintained by a combined approach of automated analyses, collaboration and manual curation to generate an up-to-date representation of the sequence, its features, names and cross-links to related sources of information. We report here on recent growth, the status of curating the human RefSeq data set, more extensive feature annotation and current policy for eukaryotic genome annotation via the NCBI annotation pipeline. More information about the resource is available online (see http://www.ncbi.nlm.nih.gov/RefSeq/).
Reference Key
openalex_W2042160423 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kim D. Pruitt, Tatiana Tatusova, Garth Brown, Donna Maglott
Journal Nucleic Acids Research
Year 2011
DOI
10.1093/nar/gkr1079
URL
https://academic.oup.com/nar/article-pdf/40/D1/D130/9478156/gkr1079.pdf
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