GOSemSim: an R package for measuring semantic similarity among GO terms and gene products

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ID: 296120
2010
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Abstract
Abstract Summary: The semantic comparisons of Gene Ontology (GO) annotations provide quantitative ways to compute similarities between genes and gene groups, and have became important basis for many bioinformatics analysis approaches. GOSemSim is an R package for semantic similarity computation among GO terms, sets of GO terms, gene products and gene clusters. Four information content (IC)- and a graph-based methods are implemented in the GOSemSim package, multiple species including human, rat, mouse, fly and yeast are also supported. The functions provided by the GOSemSim offer flexibility for applications, and can be easily integrated into high-throughput analysis pipelines. Availability: GOSemSim is released under the GNU General Public License within Bioconductor project, and freely available at http://bioconductor.org/packages/2.6/bioc/html/GOSemSim.html Contact: boxc@bmi.ac.cn; sqwang@bmi.ac.cn Supplementary information: Supplementary information is available at Bioinformatics online.
Reference Key
openalex_W2100761975 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Guangchuang Yu, Fei Li, Yide Qin, Xiaochen Bo, Yibo Wu, Shengqi Wang
Journal BMC Bioinformatics
Year 2010
DOI
10.1093/bioinformatics/btq064
URL
https://academic.oup.com/bioinformatics/article-pdf/26/7/976/48856720/bioinformatics_26_7_976.pdf
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