AUGUSTUS: a web server for gene finding in eukaryotes

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ID: 295777
2004
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Abstract
We present a www server for AUGUSTUS, a novel software program for ab initio gene prediction in eukaryotic genomic sequences. Our method is based on a generalized Hidden Markov Model with a new method for modeling the intron length distribution. This method allows approximation of the true intron length distribution more accurately than do existing programs. For genomic sequence data from human and Drosophila melanogaster, the accuracy of AUGUSTUS is superior to existing gene-finding approaches. The advantage of our program becomes apparent especially for larger input sequences containing more than one gene. The server is available at http://augustus.gobics.de.
Reference Key
openalex_W2118970397 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Mario Stanke, Ralph Steinkamp, Stephan Waack, Burkhard Morgenstern
Journal Nucleic Acids Research
Year 2004
DOI
10.1093/nar/gkh379
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