TRANSFAC: an integrated system for gene expression regulation

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Abstract
TRANSFAC is a database on transcription factors, their genomic binding sites and DNA-binding profiles (http://transfac.gbf.de/TRANSFAC/ ). Its content has been enhanced, in particular by information about training sequences used for the construction of nucleotide matrices as well as by data on plant sites and factors. Moreover, TRANSFAC has been extended by two new modules: PathoDB provides data on pathologically relevant mutations in regulatory regions and transcription factor genes, whereas S/MARt DB compiles features of scaffold/matrix attached regions (S/MARs) and the proteins binding to them. Additionally, the databases TRANSPATH, about signal transduction, and CYTOMER, about organs and cell types, have been extended and are increasingly integrated with the TRANSFAC data sources.
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openalex_W2142890842 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Edgar Wingender
Journal Nucleic Acids Research
Year 2000
DOI
10.1093/nar/28.1.316
URL
https://academic.oup.com/nar/article-pdf/28/1/316/9895171/280316.pdf
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