Tectonic control of chemical and isotopic composition of ancient oceans; the impact of continental growth

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2000
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Abstract
Herpes simplex encephalitis (HSE) is the most frequent cause of sporadic fatal encephalitis in the Western world. Definitive diagnosis by viral PCR of cerebrospinal fluid (CSF) and treatment with aciclovir have improved the prognosis significantly. Nevertheless, the condition is rare and presents with non-specific symptoms that can easily be mistaken for systemic infection or non-infective encephalopathy. We report a case of HSE which was not recognised by four separate doctors, leading to substantial delay in diagnosis and treatment. Our patient presented with fever, headaches, altered behaviour and generalised bradykinesia. This was initially diagnosed as otitis interna (labyrinthitis) and, subsequently, an ischaemic stroke. There was a delay of 10 days in the initiation of aciclovir from symptom onset. MRI and CSF PCR confirmed herpes simplex virus type-1 (HSV-1) infection. The patient improved on aciclovir, but is disabled with word-finding difficulties and cognitive slowing.
Reference Key
openalex_W2000996376 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yves Godderis
Journal american journal of science
Year 2000
DOI
10.2475/ajs.300.5.434
URL
https://doi.org/10.2475/ajs.300.5.434
Keywords Keywords not found

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