VFDB 2016: hierarchical and refined dataset for big data analysis—10 years on

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ID: 292434
2015
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Abstract
The virulence factor database (VFDB, http://www.mgc.ac.cn/VFs/) is dedicated to providing up-to-date knowledge of virulence factors (VFs) of various bacterial pathogens. Since its inception the VFDB has served as a comprehensive repository of bacterial VFs for over a decade. The exponential growth in the amount of biological data is challenging to the current database in regard to big data analysis. We recently improved two aspects of the infrastructural dataset of VFDB: (i) removed the redundancy introduced by previous releases and generated two hierarchical datasets – one core dataset of experimentally verified VFs only and another full dataset including all known and predicted VFs and (ii) refined the gene annotation of the core dataset with controlled vocabularies. Our efforts enhanced the data quality of the VFDB and promoted the usability of the database in the big data era for the bioinformatic mining of the explosively growing data regarding bacterial VFs.
Reference Key
openalex_W2173913502 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Lihong Chen, Dandan Zheng, Bo Liu, Jian Yang, Qi Jin
Journal Nucleic Acids Research
Year 2015
DOI
10.1093/nar/gkv1239
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