miRecords: an integrated resource for microRNA-target interactions

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ID: 292330
2008
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Abstract
MicroRNAs (miRNAs) are an important class of small noncoding RNAs capable of regulating other genes' expression. Much progress has been made in computational target prediction of miRNAs in recent years. More than 10 miRNA target prediction programs have been established, yet, the prediction of animal miRNA targets remains a challenging task. We have developed miRecords, an integrated resource for animal miRNA–target interactions. The Validated Targets component of this resource hosts a large, high-quality manually curated database of experimentally validated miRNA–target interactions with systematic documentation of experimental support for each interaction. The current release of this database includes 1135 records of validated miRNA–target interactions between 301 miRNAs and 902 target genes in seven animal species. The Predicted Targets component of miRecords stores predicted miRNA targets produced by 11 established miRNA target prediction programs. miRecords is expected to serve as a useful resource not only for experimental miRNA researchers, but also for informatics scientists developing the next-generation miRNA target prediction programs. The miRecords is available at http://miRecords.umn.edu/miRecords.
Reference Key
openalex_W2134118500 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Feifei Xiao, Zhixiang Zuo, Guoping Cai, Seok Yun Kang, Xiaolian Gao, Tianhao Li
Journal Nucleic Acids Research
Year 2008
DOI
10.1093/nar/gkn851
URL
https://doi.org/10.1093/nar/gkn851
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