HAND AND SEX DIFFERENCES IN THE ISTHMUS AND GENU OF THE HUMAN CORPUS CALLOSUM

Clicks: 4
ID: 292318
1989
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Popular

Ranked #188 of 378 articles by views in Brain research

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 378 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
SUMMARY The midsagittal area of the corpus callosum was measured in its entirety and in seven subdivisions in a sample of 50 brains consecutively obtained from autopsies of individuals who had neuropsychological testing before death. A 12-item test of hand preference was used as an index of the pattern of interhemispheric functional asymmetry. Callosal size was analysed for two factors: hand preference, classified as consistent-right-hand preference (CRH) versus non consistent-right-hand preference, and sex. The group of nCRH (n = 18) was found to have a larger overall callosal area, with the greatest difference occurring in the posterior body segments, especially the isthmus The isthmus probably includes interhemispheric fibres from posterior parietal and superior temporal cortex which involves cortical regions related to functional asymmetry. The results of variation in callosal morphology are discussed as part of a possible substrate of functional asymmetry and due to variation in axonal elimination in early brain development. Sex differences were found in several aspects of callosal anatomy. (1) The difference between hand groups in the posterior body occurred in interaction with sex: handedness was a factor in callosal size in males (n = 15), but not in females (n = 35) This result is consistent with the general hypothesis of females having less clear lateralization than males. (2) Females did not have a larger overall callosum or a larger splemum, either in absolute size or size proportional to brain weight. The latter measure was considered since callosal area correlated with cerebrum weight (r = 0.48). In contrast, females of both hand groups were found to have a larger proportional isthmus compared to CRH males. (3) Of all callosal regions, only the genu and a part of the anterior body were found to be larger in absolute size in males than females (4) Callosal size decreased with chronological age in males, but not in females.
Reference Key
openalex_W2052169203 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sandra F. Witelson
Journal Brain research
Year 1989
DOI
10.1093/brain/112.3.799
URL
https://doi.org/10.1093/brain/112.3.799
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.