NCBI GEO: mining tens of millions of expression profiles--database and tools update

Clicks: 2
ID: 292134
2006
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Abstract
The Gene Expression Omnibus (GEO) repository at the National Center for Biotechnology Information (NCBI) archives and freely disseminates microarray and other forms of high-throughput data generated by the scientific community. The database has a minimum information about a microarray experiment (MIAME)-compliant infrastructure that captures fully annotated raw and processed data. Several data deposit options and formats are supported, including web forms, spreadsheets, XML and Simple Omnibus Format in Text (SOFT). In addition to data storage, a collection of user-friendly web-based interfaces and applications are available to help users effectively explore, visualize and download the thousands of experiments and tens of millions of gene expression patterns stored in GEO. This paper provides a summary of the GEO database structure and user facilities, and describes recent enhancements to database design, performance, submission format options, data query and retrieval utilities. GEO is accessible at http://www.ncbi.nlm.nih.gov/geo/
Reference Key
openalex_W2154362705 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Tanya Barrett, D. B. Troup, S. E. Wilhite, Pierre Ledoux, Dmitry Rudnev, C. Evangelista, Irene F. Kim, А. Г. Соболева, Maxim Tomashevsky, Ron Edgar
Journal Nucleic Acids Research
Year 2006
DOI
10.1093/nar/gkl887
URL
https://doi.org/10.1093/nar/gkl887
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