Ensembl 2021

Clicks: 19
ID: 292130
2020
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Abstract
Abstract The Ensembl project (https://www.ensembl.org) annotates genomes and disseminates genomic data for vertebrate species. We create detailed and comprehensive annotation of gene structures, regulatory elements and variants, and enable comparative genomics by inferring the evolutionary history of genes and genomes. Our integrated genomic data are made available in a variety of ways, including genome browsers, search interfaces, specialist tools such as the Ensembl Variant Effect Predictor, download files and programmatic interfaces. Here, we present recent Ensembl developments including two new website portals. Ensembl Rapid Release (http://rapid.ensembl.org) is designed to provide core tools and services for genomes as soon as possible and has been deployed to support large biodiversity sequencing projects. Our SARS-CoV-2 genome browser (https://covid-19.ensembl.org) integrates our own annotation with publicly available genomic data from numerous sources to facilitate the use of genomics in the international scientific response to the COVID-19 pandemic. We also report on other updates to our annotation resources, tools and services. All Ensembl data and software are freely available without restriction.
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Authors Kevin Howe, Premanand Achuthan, James E. Allen, Jamie Allen, Jorge Álvarez-Jarreta, M Ridwan Amode, Irina M. Armean, Andrey G Azov, Ruth Bennett, Jyothish Bhai, Konstantinos Billis, Sanjay Boddu, Mehrnaz Charkhchi, Carla Cummins, Luca Da Rin Fioretto, Claire Davidson, Kamalkumar Dodiya, Bilal El Houdaigui, Reham Fatima, Astrid Gall, Carlos García Girón, Tiago Grego, Cristina Guijarro-Clarke, Leanne Haggerty, Anmol Jaywant Hemrom, Thibaut Hourlier, Osagie Izuogu, Thomas Juettemann, Vinay Kaikala, Mike Kay, Ilias Lavidas, Anh Tuân Lê, Diana Lemos, José M. González, José Carlos Marugán, Thomas Maurel, Aoife McMahon, Shamika Mohanan, Benjamin Moore, Matthieu Muffato, Denye N Oheh, Dimitrios Paraschas, Anne Parker, Andrew Parton, Irina Prosovetskaia, Manoj Pandian Sakthivel, Ahamed Imran Abdul Salam, Bianca M. Schmitt, Helen Schuilenburg, Dan Sheppard, Emily Steed, Michał Szpak, M. Szuba, Kieron Taylor, Anja Thormann, Glen Threadgold, Brandon Walts, Andrea Winterbottom, Marc Chakiachvili, Ameya Chaubal, Nishadi De Silva, Bethany Flint, Adam Frankish, Sarah Hunt, Garth R IIsley, Nicholas Langridge, Jane Loveland, Fergal J. Martin, Jonathan M. Mudge, Joanella Morales, Emily Perry, Magali Ruffier, John Tate, David Thybert, Stephen J. Trevanion, Fiona Cunningham, Andrew Yates, Daniel R. Zerbino, Paul Flicek
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Journal Nucleic Acids Research
Year 2020
DOI
10.1093/nar/gkaa942
URL
https://academic.oup.com/nar/article-pdf/49/D1/D884/35364073/gkaa942.pdf
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