Rfam: annotating non-coding RNAs in complete genomes

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ID: 291830
2004
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Abstract
Rfam is a comprehensive collection of non-coding RNA (ncRNA) families, represented by multiple sequence alignments and profile stochastic context-free grammars. Rfam aims to facilitate the identification and classification of new members of known sequence families, and distributes annotation of ncRNAs in over 200 complete genome sequences. The data provide the first glimpses of conservation of multiple ncRNA families across a wide taxonomic range. A small number of large families are essential in all three kingdoms of life, with large numbers of smaller families specific to certain taxa. Recent improvements in the database are discussed, together with challenges for the future. Rfam is available on the Web at http://www.sanger.ac.uk/Software/Rfam/ and http://rfam.wustl.edu/ .
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openalex_W2042881722 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sam Griffiths‐Jones
Journal Nucleic Acids Research
Year 2004
DOI
10.1093/nar/gki081
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