ScanProsite: detection of PROSITE signature matches and ProRule-associated functional and structural residues in proteins

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ID: 291763
2006
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Abstract
ScanProsite— http://www.expasy.org/tools/scanprosite/ —is a new and improved version of the web-based tool for detecting PROSITE signature matches in protein sequences. For a number of PROSITE profiles, the tool now makes use of ProRules—context-dependent annotation templates—to detect functional and structural intra-domain residues. The detection of those features enhances the power of function prediction based on profiles. Both user-defined sequences and sequences from the UniProt Knowledgebase can be matched against custom patterns, or against PROSITE signatures. To improve response times, matches of sequences from UniProtKB against PROSITE signatures are now retrieved from a pre-computed match database. Several output modes are available including simple text views and a rich mode providing an interactive match and feature viewer with a graphical representation of results.
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openalex_W2125079066 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Edouard de Castro, Christian Sigrist, Alexandre Gattiker, V. Bulliard, Petra Langendijk-Genevaux, Elisabeth Gasteiger, Amos Bairoch, N. Hulo
Journal Nucleic Acids Research
Year 2006
DOI
10.1093/nar/gkl124
URL
https://academic.oup.com/nar/article-pdf/34/suppl_2/W362/7622814/gkl124.pdf
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