TISIDB: an integrated repository portal for tumor–immune system interactions

Clicks: 33
ID: 291011
2019
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #188 of 983 articles by views in BMC Bioinformatics

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 983 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
The interaction between tumor and immune system plays a crucial role in both cancer development and treatment response. To facilitate comprehensive investigation of tumor-immune interactions, we have designed a user-friendly web portal TISIDB, which integrated multiple types of data resources in oncoimmunology. First, we manually curated 4176 records from 2530 publications, which reported 988 genes related to anti-tumor immunity. Second, genes associated with the resistance or sensitivity of tumor cells to T cell-mediated killing and immunotherapy were identified by analyzing high-throughput screening and genomic profiling data. Third, associations between any gene and immune features, such as lymphocytes, immunomodulators and chemokines, were pre-calculated for 30 TCGA cancer types. In TISIDB, biologists can cross-check a gene of interest about its role in tumor-immune interactions through literature mining and high-throughput data analysis, and generate testable hypotheses and high quality figures for publication.http://cis.hku.hk/TISIDB.Supplementary data are available at Bioinformatics online.
Reference Key
openalex_W2937441321 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Beibei Ru, Ching Ngar Wong, Yin Tong, Jia Zhong, Sophia Shek Wa Zhong, Wai Chung Wu, Ka Chi Chu, Choi Yiu Wong, Chit Ying Lau, Ian Chen, Nam Wai Chan, Jiangwen Zhang
Are you one of these authors? Claim your profile
Journal BMC Bioinformatics
Year 2019
DOI
10.1093/bioinformatics/btz210
URL
https://doi.org/10.1093/bioinformatics/btz210
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.