IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content

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ID: 291003
2005
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Abstract
Summary: Intrinsically unstructured/disordered proteins and domains (IUPs) lack a well-defined three-dimensional structure under native conditions. The IUPred server presents a novel algorithm for predicting such regions from amino acid sequences by estimating their total pairwise interresidue interaction energy, based on the assumption that IUP sequences do not fold due to their inability to form sufficient stabilizing interresidue interactions. Optional to the prediction are built-in parameter sets optimized for predicting short or long disordered regions and structured domains. Availability: The IUPred server is available for academic users at http://iupred.enzim.hu Contact: zsuzsa@enzim.hu
Reference Key
openalex_W2156407548 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zsuzsanna Dosztányi, Veronika Csizmók, Péter Tompa, István Simon
Journal BMC Bioinformatics
Year 2005
DOI
10.1093/bioinformatics/bti541
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