tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes

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ID: 290386
2016
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Abstract
High-throughput genome sequencing continues to grow the need for rapid, accurate genome annotation and tRNA genes constitute the largest family of essential, ever-present non-coding RNA genes. Newly developed tRNAscan-SE 2.0 has advanced the state-of-the-art methodology in tRNA gene detection and functional prediction, captured by rich new content of the companion Genomic tRNA Database. Previously, web-server tRNA detection was isolated from knowledge of existing tRNAs and their annotation. In this update of the tRNAscan-SE On-line resource, we tie together improvements in tRNA classification with greatly enhanced biological context via dynamically generated links between web server search results, the most relevant genes in the GtRNAdb and interactive, rich genome context provided by UCSC genome browsers. The tRNAscan-SE On-line web server can be accessed at http://trna.ucsc.edu/tRNAscan-SE/.
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openalex_W2393535458 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Todd M. Lowe, Patricia P. Chan
Journal Nucleic Acids Research
Year 2016
DOI
10.1093/nar/gkw413
URL
https://academic.oup.com/nar/article-pdf/44/W1/W54/7634746/gkw413.pdf
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