Frailty in Relation to the Accumulation of Deficits

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ID: 290349
2007
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Ranked #71 of 129 articles by views in the journals of gerontology series a, biological sciences and medical sciences

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Abstract
This review article summarizes how frailty can be considered in relation to deficit accumulation. Recalling that frailty is an age-associated, nonspecific vulnerability, we consider symptoms, signs, diseases, and disabilities as deficits, which are combined in a frailty index. An individual's frailty index score reflects the proportion of potential deficits present in that person, and indicates the likelihood that frailty is present. Although based on a simple count, the frailty index shows several interesting properties, including a characteristic rate of accumulation, a submaximal limit, and characteristic changes with age in its distribution. The frailty index, as a state variable, is able to quantitatively summarize vulnerability. Future studies include the application of network analyses and stochastic analytical techniques to the evaluation of the frailty index and the description of other state variables in relation to frailty.
Reference Key
openalex_W2129700906 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kenneth Rockwood, Arnold Mitnitski
Journal the journals of gerontology series a, biological sciences and medical sciences
Year 2007
DOI
10.1093/gerona/62.7.722
URL
https://doi.org/10.1093/gerona/62.7.722
Keywords Keywords not found

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