deepTools: a flexible platform for exploring deep-sequencing data

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ID: 289946
2014
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Abstract
We present a Galaxy based web server for processing and visualizing deeply sequenced data. The web server's core functionality consists of a suite of newly developed tools, called deepTools, that enable users with little bioinformatic background to explore the results of their sequencing experiments in a standardized setting. Users can upload pre-processed files with continuous data in standard formats and generate heatmaps and summary plots in a straight-forward, yet highly customizable manner. In addition, we offer several tools for the analysis of files containing aligned reads and enable efficient and reproducible generation of normalized coverage files. As a modular and open-source platform, deepTools can easily be expanded and customized to future demands and developments. The deepTools webserver is freely available at http://deeptools.ie-freiburg.mpg.de and is accompanied by extensive documentation and tutorials aimed at conveying the principles of deep-sequencing data analysis. The web server can be used without registration. deepTools can be installed locally either stand-alone or as part of Galaxy.
Reference Key
openalex_W2158789637 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Fidel Ramírez, Friederike Dündar, Sarah Diehl, Björn Grüning, Thomas Manke
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Journal Nucleic Acids Research
Year 2014
DOI
10.1093/nar/gku365
URL
https://academic.oup.com/nar/article-pdf/42/W1/W187/17423011/gku365.pdf
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