MEGA: A biologist-centric software for evolutionary analysis of DNA and protein sequences

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ID: 289875
2008
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Abstract
The Molecular Evolutionary Genetics Analysis (MEGA) software is a desktop application designed for comparative analysis of homologous gene sequences either from multigene families or from different species with a special emphasis on inferring evolutionary relationships and patterns of DNA and protein evolution. In addition to the tools for statistical analysis of data, MEGA provides many convenient facilities for the assembly of sequence data sets from files or web-based repositories, and it includes tools for visual presentation of the results obtained in the form of interactive phylogenetic trees and evolutionary distance matrices. Here we discuss the motivation, design principles and priorities that have shaped the development of MEGA. We also discuss how MEGA might evolve in the future to assist researchers in their growing need to analyze large data set using new computational methods.
Reference Key
openalex_W2110899053 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sudhir Kumar, M Nei, Joel T. Dudley, Koichiro Tamura
Journal Briefings in bioinformatics
Year 2008
DOI
10.1093/bib/bbn017
URL
https://academic.oup.com/bib/article-pdf/9/4/299/742560/bbn017.pdf
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