GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

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ID: 289733
2019
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Abstract
Abstract Introduced in 2017, the GEPIA (Gene Expression Profiling Interactive Analysis) web server has been a valuable and highly cited resource for gene expression analysis based on tumor and normal samples from the TCGA and the GTEx databases. Here, we present GEPIA2, an updated and enhanced version to provide insights with higher resolution and more functionalities. Featuring 198 619 isoforms and 84 cancer subtypes, GEPIA2 has extended gene expression quantification from the gene level to the transcript level, and supports analysis of a specific cancer subtype, and comparison between subtypes. In addition, GEPIA2 has adopted new analysis techniques of gene signature quantification inspired by single-cell sequencing studies, and provides customized analysis where users can upload their own RNA-seq data and compare them with TCGA and GTEx samples. We also offer an API for batch process and easy retrieval of the analysis results. The updated web server is publicly accessible at http://gepia2.cancer-pku.cn/.
Reference Key
openalex_W2946657092 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zefang Tang, Boxi Kang, Chenwei Li, Tianxiang Chen, Zemin Zhang
Journal Nucleic Acids Research
Year 2019
DOI
10.1093/nar/gkz430
URL
https://academic.oup.com/nar/article-pdf/47/W1/W556/28879658/gkz430.pdf
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