PEAR: a fast and accurate Illumina Paired-End reAd mergeR

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ID: 289641
2013
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Abstract
Motivation: The Illumina paired-end sequencing technology can generate reads from both ends of target DNA fragments, which can subsequently be merged to increase the overall read length. There already exist tools for merging these paired-end reads when the target fragments are equally long. However, when fragment lengths vary and, in particular, when either the fragment size is shorter than a single-end read, or longer than twice the size of a single-end read, most state-of-the-art mergers fail to generate reliable results. Therefore, a robust tool is needed to merge paired-end reads that exhibit varying overlap lengths because of varying target fragment lengths.
Reference Key
openalex_W2128711701 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Jiajie Zhang, Kassian Kobert, Tomáš Flouri, Alexandros Stamatakis
Journal BMC Bioinformatics
Year 2013
DOI
10.1093/bioinformatics/btt593
URL
https://academic.oup.com/bioinformatics/article-pdf/30/5/614/48919224/bioinformatics_30_5_614.pdf
Keywords Keywords not found

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