MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization

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ID: 289309
2017
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Ranked #49 of 57 articles by views in Briefings in bioinformatics

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Abstract
This article describes several features in the MAFFT online service for multiple sequence alignment (MSA). As a result of recent advances in sequencing technologies, huge numbers of biological sequences are available and the need for MSAs with large numbers of sequences is increasing. To extract biologically relevant information from such data, sophistication of algorithms is necessary but not sufficient. Intuitive and interactive tools for experimental biologists to semiautomatically handle large data are becoming important. We are working on development of MAFFT toward these two directions. Here, we explain (i) the Web interface for recently developed options for large data and (ii) interactive usage to refine sequence data sets and MSAs.
Reference Key
openalex_W2751583588 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kazutaka Katoh, John Rozewicki, Kazunori Yamada
Journal Briefings in bioinformatics
Year 2017
DOI
10.1093/bib/bbx108
URL
https://academic.oup.com/bib/article-pdf/20/4/1160/30119669/bbx108.pdf
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