BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs
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ID: 289173
2015
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Abstract
Genomics has revolutionized biological research, but quality assessment of the resulting assembled sequences is complicated and remains mostly limited to technical measures like N50.We propose a measure for quantitative assessment of genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. We implemented the assessment procedure in open-source software, with sets of Benchmarking Universal Single-Copy Orthologs, named BUSCO.Software implemented in Python and datasets available for download from http://busco.ezlab.org.evgeny.zdobnov@unige.chSupplementary data are available at Bioinformatics online.
| Reference Key |
openalex_W2155628349
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|---|---|
| Authors | Felipe A. Simão, Robert M. Waterhouse, Panagiotis Ioannidis, Evgenia V. Kriventseva, Evgeny M. Zdobnov |
| Journal | BMC Bioinformatics |
| Year | 2015 |
| DOI |
10.1093/bioinformatics/btv351
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| URL | |
| Keywords | Keywords not found |
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