The Pfam protein families database.

Clicks: 1
ID: 289145
2002
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Abstract
Pfam is a large collection of protein multiple sequence alignments and profile hidden Markov models. Pfam is available on the World Wide Web in the UK at http://www.sanger.ac.uk/Software/Pfam/, in Sweden at http://www.cgb.ki.se/Pfam/, in France at http://pfam.jouy.inra.fr/ and in the US at http://pfam.wustl.edu/. The latest version (6.6) of Pfam contains 3071 families, which match 69% of proteins in SWISS-PROT 39 and TrEMBL 14. Structural data, where available, have been utilised to ensure that Pfam families correspond with structural domains, and to improve domain-based annotation. Predictions of non-domain regions are now also included. In addition to secondary structure, Pfam multiple sequence alignments now contain active site residue mark-up. New search tools, including taxonomy search and domain query, greatly add to the functionality and usability of the Pfam resource.
Reference Key
openalex_W2141885858 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Alex Bateman, Ewan Birney, Lorenzo Cerruti, Richard Durbin, Laurence Etwiller, Sean R. Eddy, Sam Griffiths‐Jones, Kevin Howe, Mhairi Marshall, Erik L L Sonnhammer
Journal Nucleic Acids Research
Year 2002
DOI
10.1093/nar/30.1.276
URL
https://academic.oup.com/nar/article-pdf/38/suppl_1/D211/11218375/gkp985.pdf
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