Synthesis, characterization and biological properties of cobalt(II) complexes of 1,10-phenanthroline and maltol.
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ID: 2839
2011
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Abstract
The synthesis and characterization of two cobalt(II) complexes, Co(phen)(ma)Cl 1 and Co(ma)(2)(phen) 2, (phen=1,10-phenanthroline, ma(-)=maltolate or 2-methyl-4-oxo-4H-pyran-3-olate) are reported herein. The complexes have been characterized by FTIR, CHN analysis, fluorescence spectroscopy, UV-visible spectroscopy, conductivity measurement and X-ray crystallography. The number of chelated maltolate ligands seems to influence their DNA recognition, topoisomerase I inhibition and antiproliferative properties.
| Reference Key |
chin2011synthesisjournal
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| Authors | Chin, Lee Fang;Kong, Siew Ming;Seng, Hoi Ling;Khoo, Kong Soo;Vikneswaran, Rajamurthy;Teoh, Siang Guan;Ahmad, Munirah;Khoo, Soo Beng Alan;Maah, Mohd Jamil;Ng, Chew Hee; |
| Journal | Journal of inorganic biochemistry |
| Year | 2011 |
| DOI |
10.1016/j.jinorgbio.2010.11.018
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| URL | |
| Keywords | Keywords not found |
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