Oral fluid versus blood in HIV self-testing: A step towards "95-95-95" targets of the UNAIDS?

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ID: 282396
2025
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Abstract
The population of HIV-infected individuals who are not aware of their HIV status or who do not usually have access to HIV services should be reached by the newer strategies. The WHO's guideline on HIV self-testing (HIV-ST) was based on a boost in the number of tests administered in randomized clinical trials, including those carried out among the general population in regions with a high HIV burden. Therefore, HIV-ST offers tremendous potential as a strategy to enhance testing frequency and improve access to HIV testing among key high-risk populations and their partners. Recent studies have documented that HIV-ST with oral fluid is perceived as a more convenient and also preferred option than using the finger prick blood-based testing due to "fear of prick", and have also reported of user's error with finger prick blood-based tests increasing than oral fluid-based test. The major benefit of oral fluid-based HIV-ST is that it makes it easier for first-time users to access testing and is more likely to increase testing frequency among key high-risk populations. The current review summarizes the pros and cons of the HIV-ST devices.
Reference Key
balakrishnan2025oral Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Balakrishnan, Pachamuthu; Vignesh, Ramachandran; Ganesh, Pitchaipillai Sankar; Shanmugam, Saravanan; Kannan, Iyanar; Sivamalar, Sathasivam; Raju, Sivadoss; Velu, Vijayakumar; Shankar, Esaki M; Sucharitha, Sree T
Journal Diagnostic microbiology and infectious disease
Year 2025
DOI
10.1016/j.diagmicrobio.2025.116867
URL
Keywords
hiv/aids hiv self-testing hiv home-based testing oral fluid hiv testing unaids “95-95-95“ targets

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