Siderophore piracy enhances environmental survival and pathogenesis.
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ID: 275130
2020
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Abstract
the aetiological agent of cholera, possesses multiple iron acquisition systems, including those for the transport of siderophores. How these systems benefit in low-iron, polymicrobial communities in environmental settings or during infection remains poorly understood. Here, we demonstrate that in iron-limiting conditions, co-culture of with a number of individual siderophore-producing microbes significantly promoted growth . We further show that in the host environment with low iron, colonizes better in adult mice in the presence of the siderophore-producing commensal . Taken together, our results suggest that in aquatic reservoirs or during infection, may overcome environmental and host iron restriction by hijacking siderophores from other microbes.
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byun2020siderophoremicrobiology
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| Authors | Byun, Hyuntae;Jung, I-Ji;Chen, Jiandong;Larios Valencia, Jessie;Zhu, Jay; |
| Journal | Microbiology (Reading, England) |
| Year | 2020 |
| DOI |
10.1099/mic.0.000975
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