Hypothermia is not neuroprotective after infection-sensitized neonatal hypoxic-ischemic brain injury

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2014
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Abstract
Therapeutic hypothermia is not neuroprotective in this LPS-sensitized unilateral stroke-like HI brain injury model in newborn rats. Lack of neuroprotection was particularly seen in the hippocampus. Pre-insult exposure to LPS also induced brain area loss in the unligated hemisphere, which is normally …
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Authors Osredkar D;Thoresen M;Maes E;Flatebø T;Elstad M;Sabir H;;
Journal Resuscitation
Year 2014
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/24361672
Keywords
immunization National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't female male Disease Models Animal newborn Rats lipopolysaccharides wistar hippocampus / pathology brain / pathology escherichia coli hypoxia-ischemia hypothermia induced* pmid:24361672 doi:10.1016/j.resuscitation.2013.12.006 damjan osredkar marianne thoresen hemmen sabir brain / etiology brain / prevention & control*

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