Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate

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ID: 272074
2001
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Abstract
The budding of the urogenital sinus epithelium into the surrounding mesenchyme signals the onset of prostate morphogenesis. The epithelial and mesenchymal factors that regulate ductal budding and the ensuing process of ductal growth and branching are not fully known. We provide evidence that bone mo …
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Authors Lamm ML;Podlasek CA;Barnett DH;Lee J;Clemens JQ;Hebner CM;Bushman W;;
Journal Developmental biology
Year 2001
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11401393
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice gene expression regulation animals pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't male P.H.S. Inbred BALB C Base Sequence Knockout in vitro techniques in situ hybridization developmental cell division / drug effects dna primers / genetics morphogenesis / genetics heterozygote bone morphogenetic proteins / physiology* mutant strains mesoderm / cytology epithelial cells / drug effects prostate / drug effects bone morphogenetic protein 4 bone morphogenetic proteins / genetics prostate / embryology* pmid:11401393 doi:10.1006/dbio.2001.0187 m l lamm c a podlasek w bushman bone morphogenetic proteins / pharmacology morphogenesis / drug effects morphogenesis / physiology

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