A mechanism for the suppression of estrogen production in polycystic ovary syndrome

Clicks: 331
ID: 271413
1996
Free PDF
Article Quality & Performance Metrics
Overall Quality Improving Quality
0.0 /100
Combines engagement data with AI-assessed academic quality
AI Quality Assessment
Not analyzed
Abstract
In polycystic ovary syndrome (PCOS), follicle development arrests in the early antral stage when aromatase expression in the granulosa cells (GC) would normally occur. Despite high intrafollicular concentrations of androstenedione and bioactive FSH, in vivo estrogen biosynthesis remains low. When GC …
Reference Key
sk1996thea Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Agarwal SK;Judd HL;Magoffin DA;;
Journal the journal of clinical endocrinology and metabolism
Year 1996
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8855823
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't adult female adolescent P.H.S. Cells Cultured Polycystic Ovary Syndrome / metabolism* testosterone / pharmacology granulosa cells / drug effects granulosa cells / metabolism Aromatase / metabolism pmid:8855823 doi:10.1210/jcem.81.10.8855823 s k agarwal h l judd d a magoffin androstenedione / pharmacology aromatase inhibitors enzyme inhibitors estradiol / biosynthesis estrogen antagonists / metabolism* estrogens / biosynthesis* etiocholanolone / analogs & derivatives* etiocholanolone / blood etiocholanolone / metabolism etiocholanolone / pharmacology follicular fluid / chemistry follicular fluid / physiology

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.