Early prenatal androgenization results in diminished ovarian reserve in adult female rhesus monkeys

Clicks: 160
ID: 271308
2009
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Abstract
Early prenatal androgenization (PA) accelerates follicle differentiation and impairs embryogenesis in adult female rhesus monkeys (Macaca mulatta) undergoing FSH therapy for IVF. To determine whether androgen excess in utero affects follicle development ...
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Authors D.A. Dumesic, M.S. Patankar, D.K. Barnett, T.G. Lesnick, B.A. Hutcherson, D.H. Abbott;D.A. Dumesic;M.S. Patankar;D.K. Barnett;T.G. Lesnick;B.A. Hutcherson;D.H. Abbott;
Journal human reproduction (oxford, england)
Year 2009
DOI
10.1093/humrep/dep324
URL
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777787
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine pregnancy research support non-u.s. gov't female N.I.H. Extramural d a dumesic d h abbott macaca mulatta prenatal exposure delayed effects* gestational age recombinant proteins / pharmacology ovary / drug effects aging / blood fertilization in vitro virilism / blood testosterone propionate / pharmacology pmid:19740899 pmc2777787 doi:10.1093/humrep/dep324 m s patankar anti-mullerian hormone / blood* embryo culture techniques follicle stimulating hormone human / pharmacology oocyte retrieval / statistics & numerical data ovary / physiology* ovulation induction virilism / chemically induced virilism / physiopathology*

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