Resistance to macrolides in clinical isolates of Streptococcus pyogenes due to ribosomal mutations

Clicks: 338
ID: 271185
2002
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Abstract
Mutations at a similar position in ribosomal protein L4 and 23S rRNA have been reported previously in macrolide-resistant pneumococci. This report shows that similar mutations can be found in macrolide-resistant S. pyogenes.
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Authors Malbruny B;Nagai K;Coquemont M;Bozdogan B;Andrasevic AT;Hupkova H;Leclercq R;Appelbaum PC;;
Journal The Journal of antimicrobial chemotherapy
Year 2002
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/12039885
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine adult Infant drug resistance sequence homology amino acid anti-bacterial agents / pharmacology* streptococcus pyogenes / isolation & purification streptococcal infections / microbiology streptococcus pyogenes / drug effects* microbial sensitivity tests / methods macrolides streptococcal infections / drug therapy bacterial / genetics* mutation / genetics* streptococcus pyogenes / genetics* pmid:12039885 doi:10.1093/jac/dkf038 brigitte malbruny kensuke nagai peter c appelbaum microbial sensitivity tests / statistics & numerical data ribosomal proteins / genetics*

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