Endocrine antecedents of polycystic ovary syndrome in fetal and infant prenatally androgenized female rhesus monkeys

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ID: 269066
2008
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Abstract
Experimentally induced fetal androgen excess induces polycystic ovary syndrome-like traits in adult female rhesus monkeys (Macaca mulatta). Developmental changes leading to this endocrinopathy are not known. We therefore studied 15 time-mated, gravid female rhesus monkeys with known female fetuses. …
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Authors Abbott DH;Barnett DK;Levine JE;Padmanabhan V;Dumesic DA;Jacoris S;Tarantal AF;;
Journal biology of reproduction
Year 2008
DOI
DOI not found
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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18385445
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine pregnancy research support female N.I.H. Extramural david h abbott alice f tarantal luteinizing hormone / blood polycystic ovary syndrome / chemically induced* newborn macaca mulatta polycystic ovary syndrome / physiopathology progesterone / blood androgens / pharmacology* polycystic ovary syndrome / embryology fetus / drug effects* polycystic ovary syndrome / pathology estrogens / blood pmid:18385445 pmc2531213 doi:10.1095/biolreprod.108.067702 deborah k barnett androgens / blood birth weight / drug effects endocrine system / physiopathology* fetus / pathology prenatal exposure delayed effects / blood prenatal exposure delayed effects / chemically induced* prenatal exposure delayed effects / pathology prenatal exposure delayed effects / physiopathology prenatal exposure delayed effects / veterinary virilism / blood virilism / chemically induced* virilism / pathology virilism / physiopathology

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