Analysis of Wnt gene expression in prostate cancer: mutual inhibition by WNT11 and the androgen receptor
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ID: 268614
2004
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Abstract
The Wnt signaling pathway is aberrantly activated in many tumor types, including those of the prostate, in which beta-catenin accumulates in cell nuclei and acts as a transcriptional coregulator for the androgen receptor. Because activating mutations in the beta-catenin gene are rare in prostate can …
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| Reference Key |
h2004canceranalysis
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|---|---|
| Authors | Zhu H;Mazor M;Kawano Y;Walker MM;Leung HY;Armstrong K;Waxman J;Kypta RM;; |
| Journal | Cancer research |
| Year | 2004 |
| DOI |
DOI not found
|
| URL | |
| Keywords |
Tumor
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
RNA
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
male
cell line
Receptors
transcription
disease progression
signal transduction
messenger / analysis
cell division
androgen / physiology*
wnt proteins
beta catenin
prostatic neoplasms / metabolism
prostatic neoplasms / pathology*
metribolone / pharmacology
pmid:15520198
doi:10.1158/0008-5472.can-04-2704
hanneng zhu
michal mazor
robert m kypta
cytoskeletal proteins / physiology
glycoproteins / genetics*
glycoproteins / physiology
trans-activators / physiology
|
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