Evaluation of an oral suspension of VP20621, spores of nontoxigenic Clostridium difficile strain M3, in healthy subjects

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2012
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Abstract
VP20621, spores of nontoxigenic Clostridium difficile (NTCD) strain M3, is protective against challenge with toxigenic strains in hamsters. Human administration and colonization may prevent primary C. difficile infection (CDI) or recurrent CDI. Healthy adult subjects 18 to 45 years old or ≥60 years …
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Authors Villano SA;Seiberling M;Tatarowicz W;Monnot-Chase E;Gerding DN;;
Journal Antimicrobial agents and chemotherapy
Year 2012
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/22850511##substances
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult female male adolescent middle aged young adult Randomized Controlled Trial Double-Blind Method spores bacterial / drug effects* enterocolitis vancomycin / therapeutic use* pmid:22850511 PMC3457387 doi:10.1128/AAC.00913-12 Stephen A Villano Michael Seiberling Dale N Gerding Clostridioides difficile / drug effects* Clostridioides difficile / pathogenicity* Pseudomembranous / prevention & control

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