A human prostatic epithelial model of hormonal carcinogenesis

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ID: 267896
2001
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Abstract
The effects of stromal and hormonal environment on the immortalized but nontumorigenic human prostatic epithelial cell line BPH-1 were investigated in an in vivo model. BPH-1 cells were recombined with rat urogenital sinus mesenchyme (UGM), and the tissue recombinants were grafted to the renal capsu …
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Authors Wang Y, Sudilovsky D, Zhang B, Haughney PC, Rosen MA, Wu DS, Cunha TJ, Dahiya R, Cunha GR, Hayward SW
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Journal Cancer research
Year 2001
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11507055
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals humans pubmed abstract nih national institutes of health national library of medicine pregnancy research support non-u.s. gov't u.s. gov't non-p.h.s. female male P.H.S. Rats Antigens cell line nude testosterone / toxicity* cell division / drug effects cell transformation Orchiectomy epithelial cells / pathology prostatic neoplasms / pathology pmid:11507055 y wang d sudilovsky s w hayward polyomavirus transforming / physiology apoptosis / physiology neoplastic / drug effects* neoplastic / pathology estradiol / toxicity* mesoderm / cytology mesoderm / physiology prostatic neoplasms / chemically induced* subrenal capsule assay urogenital system / cytology urogenital system / embryology urogenital system / physiology

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