Signature-tagged mutagenesis in a chicken infection model leads to the identification of a novel avian pathogenic Escherichia coli fimbrial adhesin

Clicks: 301
ID: 267793
2009
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Abstract
The extraintestinal pathogen, avian pathogenic E. coli (APEC), known to cause systemic infections in chickens, is responsible for large economic losses in the poultry industry worldwide. In order to identify genes involved in the early essential stages of pathogenesis, namely adhesion and colonizati …
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Authors Antão EM;Ewers C;Gürlebeck D;Preisinger R;Homeier T;Li G;Wieler LH;;
Journal PloS one
Year 2009
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/19907658
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't Fibroblasts / metabolism Chickens mutation microscopy dogs escherichia coli / metabolism adhesins multigene family gene deletion escherichia coli / metabolism* bacterial / metabolism* fimbriae pmid:19907658 pmc2771359 doi:10.1371/journal.pone.0007796 esther-maria antão christa ewers lothar h wieler birds escherichia coli / genetics* escherichia coli infections / metabolism* genetic complementation test electron / methods mutagenesis* respiratory infections chickens lungs bacterial pathogens adhesins animal models of infection pili and fimbriae chicken models

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