The selectivity of protein kinase inhibitors: a further update

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ID: 267548
2007
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Abstract
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases. On the basis of this information, the effects of compounds that we have studied in cells and other data in the literature, we recommend the …
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Authors Bain J;Plater L;Elliott M;Shpiro N;Hastie CJ;McLauchlan H;Klevernic I;Arthur JS;Alessi DR;Cohen P;;
Journal The Biochemical journal
Year 2007
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17850214
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't amino acid sequence cell line phosphorylation drug design pmid:17850214 pmc2267365 doi:10.1042/bj20070797 jenny bain lorna plater philip cohen enzyme activation mitogen-activated protein kinases / antagonists & inhibitors* mitogen-activated protein kinases / metabolism protein kinase inhibitors / pharmacology* recombinant proteins / antagonists & inhibitors spodoptera

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