In vitro efficacy of antibiotics commonly used to treat human plague against intracellular Yersinia pestis

Clicks: 310
ID: 267318
2011
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Abstract
Yersinia pestis initiates infection as a facultative intracellular parasite in host macrophages; however, little is known about the efficacy of antibiotics commonly used to treat human plague against intracellular Y. pestis. Intracellular minimal bactericidal concentrations (MBCs) were determined us …
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Authors Wendte JM;Ponnusamy D;Reiber D;Blair JL;Clinkenbeard KD;;
Journal Antimicrobial agents and chemotherapy
Year 2011
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/21628541
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't N.I.H. Extramural cell line microbial sensitivity tests streptomycin / pharmacology anti-bacterial agents / pharmacology* chloramphenicol / pharmacology ciprofloxacin / pharmacology gentamicins / pharmacology yersinia pestis / pathogenicity* plague / prevention & control yersinia pestis / drug effects* plague / drug therapy* amoxicillin / pharmacology pmid:21628541 pmc3147644 doi:10.1128/aac.01481-10 jered m wendte duraisamy ponnusamy kenneth d clinkenbeard doxycycline / pharmacology high-throughput screening assays / methods* macrophages / microbiology

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