Alterations in the relative amounts of specific mRNA species in the developing human brain in Down's syndrome

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1984
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Abstract
Total cellular polyadenylated RNA [poly(A)+ RNA] was prepared after guanidinium thiocyanate extraction of frozen brain tissue from age-matched normal and Down's-syndrome (trisomy 21) human foetuses. Poly(A)+ RNA populations were analysed by translation in vitro, followed by two-dimensional gel analy …
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Authors Whatley SA;Hall C;Davison AN;Lim L;;
Journal The Biochemical journal
Year 1984
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