Impact of goal-oriented and model-based clinical pharmacokinetic dosing of aminoglycosides on clinical outcome: a cost-effectiveness analysis

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1999
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Abstract
The benefits of a pharmacy-based, active therapeutic drug monitoring (TDM) service (ATM) on outcomes were examined in a prospective study at four hospitals. ATM involved pharmacokinetic dosage optimization at the start of treatment, subsequent Bayesian adaptive control, and frequent patient evaluati …
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Authors van Lent-Evers NA;Mathôt RA;Geus WP;van Hout BA;Vinks AA;;
Journal Therapeutic drug monitoring
Year 1999
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/10051056
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't female male aged Comparative Study Prospective Studies Multicenter Study anti-bacterial agents / therapeutic use length of stay outcome assessment anti-bacterial agents / administration & dosage* cost-benefit analysis* anti-bacterial agents / economics anti-bacterial agents / pharmacokinetics gram-negative bacterial infections / metabolism aminoglycosides gram-negative bacterial infections / drug therapy pmid:10051056 doi:10.1097/00007691-199902000-00010 n a van lent-evers r a mathôt a a vinks drug monitoring / economics drug monitoring / methods gram-negative bacterial infections / economics health care*

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