α-C(sp3)-H Arylation of Cyclic Carbonyl Compounds

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ID: 265885
2021
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Abstract
α-C(sp3)-H arylation is an important type of C-H functionalization. Various biologically significant natural products, chemical intermediates, and drugs have been effectively prepared via C-H functionalization. Cyclic carbonyl compounds comprise of cyclic ketones, enones, lactones, and lactams. The α-C(sp3)-H arylation of these compounds have been exhibited high efficiency in forming C(sp3)-C(sp2) bonds, played a crucial role in organic synthesis, and attracted majority of interests from organic and medicinal communities. This review focused on the most significant advances including methods, mechanism, and applications in total synthesis of natural products in the field of α-C(sp3)-H arylations of cyclic carbonyl compounds in recent years.
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wang2021naturalα-c(sp3)-h Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Mei Wang;Wei Wang;Dashan Li;Wen-Jing Wang;Rui Zhan;Li-Dong Shao;Mei Wang;Wei Wang;Dashan Li;Wen-Jing Wang;Rui Zhan;Li-Dong Shao;
Journal natural products and bioprospecting
Year 2021
DOI
doi:10.1007/s13659-021-00312-1
URL
https://link.springer.com/article/10.1007/s13659-021-00312-1
Keywords
food science Medicinal Chemistry Plant Biochemistry plant sciences bioorganic chemistry pharmacology/toxicology

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