Primitive neuroectodermal tumors of adrenal gland.

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ID: 26423
2010
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Abstract
To analyze the clinical and pathological characteristics of adrenal primitive neuroectodermal tumors for a better understanding of the disease.A retrospective analysis of four cases of adrenal primitive neuroectodermal tumors (two male, two female; age 21-30, average 24) was made. All patients went through necessary endocrinological exams, computer tomography scans (for site-specific diagnoses) and pathological tests.No positive result was reported in routine laboratory tests and endocrinological exams. Computer tomography scans showed bulk soft tissue masses with rough borders. The masses were 8-17 cm in diameter with solid-cystic changes. Among the four patients, one refused to receive treatment after definitiver diagnosis through needle biopsy, three received surgical treatments and their post-operative pathological exams all confirmed the diagnoses of primitive neuroectodermal tumors. During the follow-ups, the untreated patient died 6 months afterwards, one patient died 8 months after palliative treatment; one patient showed distant metastasis 13 months after surgery and did not respond well to both radio- and chemotherapy; one patient had local recurrence 1 month after surgery and is presently undergoing chemotherapy.Adrenal primitive neuroectodermal tumor is a very rare tumor. It originates in primitive neuroectoderma and is found mainly in 20-30-year-old young populations. It has non-specific clinical or imaging manifestation and its diagnosis is mostly based on pathological examinations. The tumor is fast-developing, highly malignant with poor prognosis.
Reference Key
zhang2010primitivejapanese Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yushi Zhang, Hanzhong Li
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Journal japanese journal of clinical oncology
Year 2010
DOI
10.1093/jjco/hyq050
URL
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