correlation between steroid receptors, angiogenic factors, and classical prognostic parameters in node-negative breast cancer patients
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ID: 259794
2009
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Abstract
Breast cancer (BC) progression is an estrogen receptor (ER) signaling- and angiogenesis-dependent process. This study investigated relationships between classical prognostic factors and biomarkers ER, PR, VEGF, and bFGF in node-negative BC patients. Positive correlation between ER and both PR (p < 0.001) or FGF (p = 0.04) levels indicates ER-regulated expression of these factors and a potential synergistic effect of ER and bFGF in tumor progression. Aside from correlation of age with ER and bFGF levels (p = 0.003; p = 0.05; respectively), no correlation of biomarkers with classical prognostic parameters was found, indicating that those biomarkers could be independent prognostic factors.
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tijana2009archivescorrelation
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| Authors | ;Vujasinović Tijana;Markićević M.;Rabi Abu Z.;Nikolić-Vukosavljević Dragica |
| Journal | gastrointestinal endoscopy |
| Year | 2009 |
| DOI |
10.2298/ABS0904599V
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