estrategia preventiva para la adicción al alcohol en gemelos: pinar del río, 2007 a strategy for the prevention of alcoholism in twins: pinar del rio, 2007

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ID: 259262
2010
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Abstract
Con el objetivo de proponer una estrategia de prevención para la adicción al alcohol en gemelos, se realizó una investigación epidemiológica, analítica y transversal (estudio en gemelos) en los meses de febrero y marzo del año 2007, en la provincia de Pinar del Río. El universo fue tomado del Registro Nacional de gemelos, estudiándose el comportamiento clínico, epidemiológico y genealógico de la adicción al alcohol en gemelos. Para la recolección de la información se confeccionó una encuesta y un árbol genealógico para cada familia. Se calculó la concordancia en gemelos, para el par y para el caso índice y la heredabilidad. Los datos se presentaron en cuadros y gráficos. Se concluyó que la mayor cantidad de los pacientes se encontraron en el grupo de mayores de 40 años de edad, del sexo masculino, en su mayoría dependientes alcohólicos. Los antecedentes familiares de alcoholismo resultaron estadísticamente significativos en el grupo de los familiares de primer grado. La concordancia fue mayor en gemelos monocigóticos que en dicigóticos y la contribución genética para el alcoholismo de 66%. Se confeccionó una estrategia de prevención del alcoholismo basada en los principios del asesoramiento genético.
Aimed at proposing a strategy for the prevention of alcoholism in twins an epidemiological, analytical and cross-sectional research was carried out during February - March 2007 in Pinar del Rio province. The universe was taken from the National Records of twins, studying clinical, epidemiological and genealogical behavior of alcohol consumption in twins. To collect the information a survey and a genealogical tree for each family were made. Also calculating twin's concordance for the par, case rate and inheritance; data were presented in tables and graphics; prevailing alcoholic patients older than 40 years old and male sex. Familial history of alcoholism resulted statistically significant in the group of first degree relatives. The concordance was greater in monozygotic than in dizygotic twins and genetic contribution for the alcoholism reached 66%. A strategy based on the principles of genetic advice to prevent alcoholism was created.
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Authors Reinaldo Menéndez García, Sulay Pereda Padilla, Deysi Licourt Otero, Gabino Ernesto Arman Aleccandrini
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Journal Frontiers in endocrinology
Year 2010
DOI
DOI not found
URL
http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-31942010000100002
Keywords
alcoholism twins

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