incretins role in latent autoimmune diabetes of adults pathogenesis, the possibility of therapy with combination of glucagon-like peptide-1 agonist (glp-1) and insulin.

Clicks: 176
ID: 259142
2016
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Abstract
Recently, the bihormonal theory of the autoimmune diabetes development is discussed in the world literature. The abnormal suppression of glucagon and reduced incretin response are considered in the development and progression of type 1 diabetes mellitus in addition to insulin deficiency. Animal studies demonstrate a GLP-1 – role in beta cell-proliferation and decrease in apoptosis. The information concerning the functioning of the incretin system in patients with type 1 diabetes and LADA is systematized in the present review. We also discuss the studies of the use of GLP-1 agonists in patients with autoimmune diabetes.
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silko2016oirenieincretins Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Iuliia V. Silko;Tatiana V. Nikonova;Marina V. Shestakova
Journal fertility and sterility
Year 2016
DOI
10.14341/omet201623-6
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