effect of protamine sulfate on the isolated mesenteric arteries of normotensive and spontaneously hypertensive rats

Clicks: 266
ID: 258840
2008
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Abstract
We tested the relaxant effect of increased protamine sulfate (PS) amounts (10, 20, 50, 100 and 150 μg/ml) on the isolated mesenteric arteries of normotensive and spontaneously hypertensive (SH) rats, with or without endothelium. PS caused concentration-dependent relaxation of isolated mesenteric arteries in both types of rats. The relaxation effect of PS was lower in SH rats than in normotensive ones. Our results indicate that the vascular smooth muscles play a significant role in PS-mediated relaxation.
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zorana2008archiveseffect Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Oreščanin-Dušić Zorana;Milovanović S.;Spasić M.;Radojičić R.;Blagojević D.
Journal gastrointestinal endoscopy
Year 2008
DOI
10.2298/ABS0802163O
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