“the mind is its own place”: amelioration of claustrophobia in semantic dementia

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ID: 258787
2014
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Ranked #55 of 78 articles by views in applied psychophysiology and biofeedback

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Abstract
Phobias are among the few intensely fearful experiences we regularly have in our everyday lives, yet the brain basis of phobic responses remains incompletely understood. Here we describe the case of a 71-year-old patient with a typical clinicoanatomical syndrome of semantic dementia led by selective (predominantly right-sided) temporal lobe atrophy, who showed striking amelioration of previously disabling claustrophobia following onset of her cognitive syndrome. We interpret our patient’s newfound fearlessness as an interaction of damaged limbic and autonomic responsivity with loss of the cognitive meaning of previously threatening situations. This case has implications for our understanding of brain network disintegration in semantic dementia and the neurocognitive basis of phobias more generally.
Reference Key
clark2014behaviouralthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Camilla N. Clark;Laura E. Downey;Hannah L. Golden;Phillip D. Fletcher;Rajith de Silva;Alberto Cifelli;Jason D. Warren
Journal applied psychophysiology and biofeedback
Year 2014
DOI
10.1155/2014/584893
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